Frequently Asked Questions (FAQs)

Read below for answers to FAQs about hepatitis C and HARVONI. If you require further assistance, speak with a HARVONI Educator at 1-844-READY41 (1-844-732-3941), or contact your Hep C Specialist.

HARVONI is a prescription medicine used with or without ribavirin to treat chronic (lasting a long time) hepatitis C genotype 1, 4, 5 or 6 infection. It is not known if HARVONI is safe and effective in children under 18 years of age.

UNDERSTANDING HEP C

Get the facts about hepatitis C, including
symptoms, effects, and the importance of genotype.

ABOUT HARVONI

Find out general information about HARVONI,
including dosing, side effects, and impact of previous
Hep C treatment.

TREATMENT WITH HARVONI

Learn about filling your prescription, understanding
insurance coverage, exploring ways to keep
out-of-pocket costs down, and more.

  • UNDERSTANDING HEP C

    Get the facts about hepatitis C, including
    symptoms, effects, and the importance of genotype.

    What is hepatitis C (Hep C) and what effects can it have?

    Hepatitis C is a contagious liver disease that ranges in severity from a mild illness lasting a few weeks to a serious, lifelong illness that attacks the liver. It results from infection with the hepatitis C virus (HCV), which is spread through contact with the blood of an infected person. Most people who become infected with the Hep C virus go on to develop chronic (or long-lasting) Hep C. Chronic Hep C progresses slowly and over time can cause liver damage or liver failure.

    If you have Hep C, you should work with your healthcare provider to assess your liver damage and discuss your treatment options before it progresses.

    To learn more about how Hep C affects your liver health, sign up for Onward™ and get free step-by-step guidance and information about Hep C.

    Sign up here
    What is cirrhosis?

    Over time, chronic Hep C can cause a type of liver damage called cirrhosis, which may eventually lead to liver failure.

    • Cirrhosis is a type of advanced liver disease in which healthy liver tissue is replaced with scar tissue
    • Liver failure (also known as decompensated cirrhosis) is when the liver is extensively scarred and can no longer do its job effectively

    To determine if you have cirrhosis, your Hep C Specialist may order a blood test, perform imaging, and/or perform a biopsy to take a closer look at your liver.

    To learn more about how Hep C affects your liver health, sign up for Onward™ and get free step-by-step guidance and information about Hep C.

    Sign up here
    What are the symptoms of Hep C?

    Called a "silent disease," Hep C symptoms often do not appear or can be quite mild for years or even decades, even while liver damage is taking place. Most people with the Hep C virus go on to develop chronic Hep C and still have no symptoms or signs. Common symptoms of chronic Hep C can include fever, tiredness, loss of appetite, nausea, vomiting, dark urine, abdominal pain, joint pain, gray-colored stools, and jaundice (yellowing of skin or eyes).

    If you'd like to learn more about Hep C symptoms, sign up for Onward™ and get free step-by-step guidance and information about treating your Hep C.

    Sign up here
    What is a Hep C genotype and why is this important?

    Just as there are different blood types, there are also different types of Hep C, called genotypes. It is important to know your genotype because it can help your healthcare provider choose the right treatment for you. It can also affect the length of your treatment and your chance of being cured. Your healthcare provider can do a simple blood test to determine your Hep C genotype. HARVONI is used to treat chronic Hep C genotype 1, 4, 5 or 6.

    If you don't have Hep C genotype 1, 4, 5, or 6, learn about another treatment option that may be right for you.

    Want to learn more?

    Visit Discover HARVONI
  • ABOUT HARVONI

    Find out general information about HARVONI,
    including dosing, side effects, and impact of previous
    Hep C treatment.

    What is HARVONI?

    HARVONI is a prescription medicine used with or without ribavirin to treat chronic (lasting a long time) hepatitis C genotype 1, 4, 5 or 6 infection. It is not known if HARVONI is safe and effective in children under 18 years of age.

    If you don't have Hep C genotype 1, 4, 5, or 6, learn about another treatment option that may be right for you.

    Want to learn more about HARVONI? Sign up for Onward™ and get free step-by-step guidance to help you get started.

    Sign up here
    How long does therapy with HARVONI last?

    Your Hep C Specialist will determine your treatment regimen and length based on your individual case. Most patient types are recommended to receive 12 weeks of treatment, although 8 or 24 weeks may also be prescribed.

    In all cases, treatment depends on the specifics of your particular situation. However, your Hep C Specialist will likely consider:

    • Your genotype
    • Whether or not you have been treated before (treatment history)
    • The level of virus in your body (viral load)
    • The presence and extent of liver damage
    • Whether or not you have had a liver transplant

    Want to know more about HARVONI treatment lengths? Learn more here.

    Not currently working with a Hep C Specialist? Find one here.

    If you don't have Hep C genotype 1, 4, 5, or 6, learn about another treatment option that may be right for you.

    Sign up for Onward™ to learn more about treatment with HARVONI and get free step-by-step guidance to help you get started.

    Sign up here
    How should I take HARVONI?

    Take HARVONI exactly as your healthcare provider tells you to take it. Do not change your dose unless your healthcare provider tells you to.

    Do not stop taking HARVONI without first talking with your healthcare provider. If you think there is a reason to stop taking HARVONI, talk to your healthcare provider before doing so.

    Take HARVONI 1 time each day and at the same time each day with or without food.

    It is important that you do not miss or skip doses of HARVONI during treatment.

    If you take too much HARVONI, call your healthcare provider or go to the nearest hospital emergency room right away.

    Want to learn more?

    Visit Treatment With HARVONI
    What should I tell my healthcare provider before taking HARVONI?
    • If you have: liver problems other than hepatitis C infection, or have had a liver transplant; severe kidney problems or are on dialysis; HIV, or any other medical condition; or if you are pregnant or breastfeeding or plan to become pregnant or breastfeed. It is not known if HARVONI will harm your unborn baby or pass into your breast milk. If you take HARVONI with ribavirin, you should also read the ribavirin Medication Guide for important pregnancy-related information.
    • Tell your healthcare provider and pharmacist about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. HARVONI and certain other medicines may affect each other, or may cause side effects. Tell your healthcare provider if you take any medicines containing tenofovir disoproxil fumarate (ATRIPLA®, COMPLERA®, STRIBILD®, TRUVADA®, VIREAD®).

    Need more help preparing to speak with your Hep C Specialist?

    Download your Conversation Guide
    Does HARVONI need to be taken with other medicines to treat Hep C?

    No additional medicines are required for the majority of patients. HARVONI is one pill, taken once daily, with or without food.

    HARVONI plus ribavirin for 12 weeks is recommended for genotype 1 patients with liver failure or for genotype 1 or 4 patients who have had a liver transplant. If you take HARVONI with ribavirin, you should also read the ribavirin Medication Guide for important pregnancy-related information.

    Take HARVONI exactly as your healthcare provider tells you to take it.

    HARVONI and certain other medicines may affect each other, or may cause side effects.

    Consult your Hep C Specialist with any treatment questions.

    Need more help preparing to speak with your Hep C Specialist?

    Download your Conversation Guide
    What are the possible side effects of HARVONI?

    HARVONI may cause serious side effects, including:

    • Slow heart rate (bradycardia). HARVONI treatment may result in slowing of the heart rate along with other symptoms when taken with amiodarone (Cordarone®, Nexterone®, Pacerone®), a medicine used to treat certain heart problems. In some cases, this has led to death or the need for a pacemaker. Get medical help right away if you take amiodarone with HARVONI and get any of the following symptoms:
      • fainting or near-fainting
      • dizziness or lightheadedness
      • not feeling well
      • weakness
      • extreme tiredness
      • shortness of breath
      • chest pains
      • confusion
      • memory problems

    The most common side effects of HARVONI include

    • tiredness
    • headache
    • weakness

    Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

    These are not all the possible side effects of HARVONI. For more information, ask your healthcare provider or pharmacist.

    Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Sign up for Onward™ and get personalized treatment tips and free step-by-step guidance to help manage side effects.

    Sign up here
    Can I take HARVONI if I was not cured with a previous Hep C treatment?

    HARVONI has been proven effective in patients with Hep C who have been unsuccessful with past Hep C treatment.

    In a study of 440 patients with genotype 1 Hep C who had failed prior Hep C therapy, 95% (83 out of 87) of patients without cirrhosis who received HARVONI once daily for 12 weeks and 100% (22 out of 22) of those patients who had cirrhosis and received HARVONI once daily for 24 weeks were cured.

    In a study of 155 patients with genotype 1 Hep C who had failed prior Hep C therapy twice and had cirrhosis, 96% (74 out of 77) of patients who received HARVONI once daily plus ribavirin for 12 weeks and 97% (75 out of 77) of patients who received HARVONI once daily without ribavirin for 24 weeks were cured.

    Cure means the Hep C virus is not detected in the blood when measured three months after treatment is completed. These studies did not include patients with liver failure or those who have had a liver transplant.

    Speak with your Hep C Specialist to find out if HARVONI is right for you.

    If you don't have Hep C genotype 1, 4, 5, or 6, learn about another treatment option that may be right for you.

    Thinking about treating your Hep C again? Sign up for Onward™ and get free step-by-step guidance to help you get started.

    Sign up here
    Can I take HARVONI if I have cirrhosis?

    Because "cirrhosis" is such a broad term, and the answer depends on certain patient characteristics, your Hep C Specialist is the best source to answer this question.

    In general, if a person does not have liver failure and has not had a liver transplant, HARVONI is recommended to treat Hep C genotypes 1, 4, 5, or 6. Your Hep C Specialist will likely consider your cirrhosis and will determine the appropriate treatment regimen and duration for you. He or she will also likely consider:

    • Your genotype (there are 6 main genotypes)
    • Whether or not you have been treated before (treatment history)
    • The level of virus in your body (viral load)

    If a person has liver failure and has genotype 1 Hep C, HARVONI plus ribavirin for 12 weeks is recommended. If you take HARVONI with ribavirin, you should also read the ribavirin Medication Guide for important pregnancy-related information.

    If you have had a liver transplant and have cirrhosis, please speak with your Hep C Specialist.

    If you don't have Hep C genotype 1, 4, 5, or 6, learn about another treatment option that may be right for you.

    If you have cirrhosis, it may not be too late to try HARVONI to treat your Hep C. Sign up for Onward™ and get free step-by-step guidance to help you get started.

    Sign up here
  • TREATMENT WITH HARVONI

    Learn about filling your prescription, understanding
    insurance coverage, exploring ways to keep
    out-of-pocket costs down, and more.

    Why is it important that I work with a Hep C Specialist?

    Hep C Specialists are experts in the treatment of hepatitis C, and they are equipped to tell you about the options that are available. Hep C Specialists include, but are not limited to, gastroenterologists (specialize in diseases that affect the digestive system) and hepatologists (specialize in diseases that affect the liver). Others who may treat Hep C include infectious diseases (ID) specialists; primary care physicians (PCPs), internal medicine specialists (internists) or family doctors; nurse practitioners (NPs), and physician assistants (PAs).

    Not currently working with a Hep C Specialist?

    Find a Hep C Specialist
    What should I bring with me when I visit my Hep C Specialist?

    When visiting your Hep C Specialist, be prepared to share your medical history. It's a good idea to bring along your medical records, a list of any and all medicines you are taking (prescription and/or over-the-counter medicines, vitamins, and herbal supplements) and write down any questions you may have for your specialist. Be prepared to talk about any symptoms you may be experiencing, even if you don't think they seem related to your liver or hepatitis C. You may wish to write down this information prior to your visit and bring it with you.

    Need more help preparing to speak with your Hep C Specialist?

    Download your Conversation Guide
    How does my Hep C Specialist determine my HARVONI treatment plan?

    Your Hep C Specialist will determine your treatment regimen and length based on your individual case. Most patient types are recommended to receive 12 weeks of treatment, although 8 or 24 weeks may also be prescribed.

    In all cases, treatment depends on the specifics of your particular situation. However, your Hep C Specialist will likely consider:

    • Your genotype
    • Whether or not you have been treated before (treatment history)
    • The level of virus in your body (viral load)
    • The presence and extent of liver damage
    • Whether or not you have had a liver transplant

    If you don't have Hep C genotype 1, 4, 5, or 6, learn about another treatment option that may be right for you.

    Want to learn more?

    Visit Treatment With HARVONI
    How do I fill my HARVONI prescription?

    If you and your Hep C Specialist decide HARVONI is right for you, your Hep C Specialist will submit your prescription directly to a specialty pharmacy. Specialty pharmacies provide medications that have special delivery, storage, or administration requirements, and typically deliver medicine directly to patients by US mail or a delivery service.

    Want to learn more? Speak with a HARVONI Support Path specialist at 1-855-7-MYPATH (1-855-769-7284).

    What is a specialty pharmacy?

    Specialty pharmacies provide medications that have special delivery, storage, or administration requirements, and deliver medicine directly to patients by US mail or a delivery service.

    Want to learn more? Speak with a HARVONI Support Path specialist at 1-855-7-MYPATH (1-855-769-7284).

    Are there ways I could save money on HARVONI?

    For information about ways you could save money on HARVONI, visit Financial Assistance & Insurance Support or call 1-855-7-MYPATH (1-855-769-7284).

    You may be eligible to pay no more than $5 per co-pay for HARVONI. Restrictions apply.

    Check your eligibility for a HARVONI co-pay coupon
    How do I find out if my insurance covers HARVONI?

    One way is by contacting HARVONI Support Path, where a specialist can assist you with this and other insurance-related questions. Call HARVONI Support Path at 1-855-7-MYPATH (1-855-769-7284) and inform the Support Path specialist that you want to complete a benefits investigation. Provide the Support Path specialist with your name and address, the name and address of your prescribing doctor, your pharmacy benefit card, and your medical benefit card. You may also contact your insurance company directly.

    Need more help preparing for your benefits investigation?

    Visit Financial Assistance & Insurance Support
    How long will it take to receive verification of my benefits from HARVONI Support Path?

    If you or your healthcare provider have contacted Support Path and requested verification of your insurance coverage, you will receive verification of your benefits in a follow-up phone call from HARVONI Support Path within 24–48 hours. Your physician will receive a written benefit verification summary via fax within 48 hours.

    Need more help navigating your insurance coverage?

    Visit Financial Assistance & Insurance Support
    What if my insurance doesn't cover HARVONI?

    You still might be eligible for financial assistance. Visit Financial Assistance & Insurance Support or speak with a HARVONI Support Path specialist at 1-855-7-MYPATH (1-855-769-7284) to see what options might be available to you.

    After I have finished treatment, how long will it take to find out if I am cured?

    Being “cured” of Hep C is defined as when the virus cannot be detected in the blood when measured at least three months after treatment is completed. Your doctor will use a simple blood test to determine your success with treatment.

    Want to learn more?

    Visit Treatment With HARVONI
    How should I store HARVONI?
    • Store HARVONI at room temperature below 86° F (30° C).
    • Keep HARVONI in its original container.
    • Do not use HARVONI if the seal over the bottle opening is broken or missing.

    Keep HARVONI and all medicines out of the reach of children.


    Need more help? Sign up for Onward™ and get personalized treatment tips and free step-by-step guidance for taking HARVONI.

    Sign up here

HARVONI is a prescription medicine used with or without ribavirin to treat chronic (lasting a long time) hepatitis C genotype 1, 4, 5 or 6 infection. It is not known if HARVONI is safe and effective in children under 18 years of age.

Important Safety Information

What should I tell my healthcare provider before taking HARVONI?

  • If you have: liver problems other than hepatitis C infection, or have had a liver transplant; severe kidney problems or are on dialysis; HIV, or any other medical condition; or if you are pregnant or breastfeeding or plan to become pregnant or breastfeed. It is not known if HARVONI will harm your unborn baby or pass into your breast milk. If you take HARVONI with ribavirin, you should also read the ribavirin Medication Guide for important pregnancy-related information.
  • Tell your healthcare provider and pharmacist about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. HARVONI and certain other medicines may affect each other, or may cause side effects. Tell your healthcare provider if you take any medicines containing tenofovir disoproxil fumarate (ATRIPLA®, COMPLERA®, STRIBILD®, TRUVADA®, VIREAD®).

What are the possible side effects of HARVONI?

  • HARVONI, when taken with amiodarone (Cordarone®, Nexterone®, Pacerone®), a medicine used to treat certain heart problems, may cause serious side effects, including slow heart rate, which in some cases has led to death or the need for a pacemaker. Get medical help right away if you take amiodarone with HARVONI and get any of the following symptoms: fainting or near-fainting, dizziness or lightheadedness, not feeling well, weakness, extreme tiredness, shortness of breath, chest pains, confusion, or memory problems.
  • The most common side effects of HARVONI include tiredness, headache and weakness.